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AstraZeneca Pharmaceuticals – Column Packing Room Addition

By fits and starts

  • 15K

    Square Feet

  • Frederick, Maryland

    Frederick, Maryland

Increasing operational space and creating a safer work environment for everyone

AstraZeneca Pharmaceuticals (formerly MedImmune) wanted to produce greater quantities of drug products and get them to market faster. But their work was being bottlenecked. After we conducted a conceptual design study, we found that one process in particular was slowing things down.

Basically, manufacturing had to stop whenever the chromatography columns were in change over. And they were in change over a lot due to shorter and more frequent manufacturing campaigns.

The solution to decreased campaign change over time was an addition—a newly designed column packing room that would remove the chromatography columns from the purification suite. Now, packing and unpacking activity would take place separate from the ongoing manufacturing processes.

The result? AstraZeneca has increased operational space in the purification suite, and the whole site delivers a safer work environment for their personnel. With the processes separated into discrete spaces, everything is more efficient.

At a Glance

Meet Our Team

David Linamen, Principal

Truly great design is a product of endless passion and intense commitment, with success measured in outcome and not in hours.

Paul Pohlod, Principal

Architects and engineers continue to merge in relentless pursuit of excellence and with collaboration and passion achieve true integration.

David Linamen


Paul Pohlod


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